OncomiRdbB-Contents

OncomiRdbB Existing databases Advantages of OncomiRdbB
miRNA
  Human

Mouse
  • PhenomiR-368
  • Mir2disease- 349 (all human diseases)
  • Microcosm-456
 microRNAs of breast cancer in two different genomes are listed.
Breast

782

246
Targets
  Human

Mouse
  • PhenomiR- No targets available
  • Mir2disease- 384(includes all human diseases)
  • microCosm- 74

Targets including major oncogenic signaling pathways.
JakStat, Wnt, Apoptosis, Notch, VEGF, MAPK, mTOR
Breast 711

490

miRNA-Target position in the gene

  • 3'utr
  • 5'utr
  • Exons
  • PhenomiR- No such details
  • Mir2disease - No such details
  • microCosm - 3'utr only
 This will help the scientific community to validate the microRNAs and its target on specific location of the genes

Location-

Chromosome wise location of each target		 Such description is not available Chromosome location of the target genes

Pathway wise Networking between miRNAs & their Targets-

  • Networking using R algorithm.
  • Regulatory network using MetaCoreTM
 such description not available Extensive network and hubs of microRNA-Target interaction - highly useful for therapeutic intervention to oncology community.