Protein Sequence-Structure Analysis Relational Database (PSSARD)

This is a database that relates on a one-to-one basis the amino acid residue and its corresponding conformation in proteins of known three-dimensional structure available in the Protein Data Bank (PDB). One can type in any peptide amino acid sequence and the corresponding conformations in all proteins of known three-dimensional structures can be retrieved. Conversely, any conformation may be specified and the amino acid sequences corresponding to the conformation in proteins of known three-dimensional structures can be retrieved. The protein PDB codes and the crystal structure resolution and the protein name for each ‘hit’ in the database is available. One can also specify the PDB entry and get the sequence and corresponding secondary structure. The native sequence in UniProt is also available. This can be used to infer if there is a difference between the native sequence and that determined by experiment. Also, amino acid residues not determined in the crystal structure can be identified.